Distinguishing signals through activity in the unstimulated third organoid
According to the report, software initially could identify the stimulated location from the resulting activity only about as often as guessing. After two weeks of repeated stimulation, that did not change for single organoids or pairs. In the three-organoid setup, however, activity in the third, unstimulated organoid reportedly became better at distinguishing which of the other two had received the signal.
The researchers interpret the result as a basic form of learning rather than anything like a complete brain's information processing. The striking mismatch is that adding a third connected tissue module, rather than simply repeating signals or growing the tissue longer, was reported to make the two signal sources distinguishable.